{"id":5930,"date":"2026-03-16T17:59:52","date_gmt":"2026-03-16T09:59:52","guid":{"rendered":"https:\/\/transactions.nast.ph\/?p=5930"},"modified":"2026-03-30T17:33:12","modified_gmt":"2026-03-30T09:33:12","slug":"dyslipidaemia-among-filipino-children-with-insulin-dependent-diabetes-mellitus-prevalence-and-relation-to-glycemic-control","status":"publish","type":"post","link":"https:\/\/transactions.nast.ph\/?p=5930","title":{"rendered":"Dyslipidaemia Among Filipino Children with Insulin-Dependent Diabetes Mellitus: Prevalence and Relation to Glycemic Control"},"content":{"rendered":"\n<p class=\"has-text-align-center\">Virginia P. Crisostomo, Carmelita F. Domingo, Lorna T. Abad, Sioksoan Cua, Sylvia Estrada, and Joseph C. Pua<br>Department of Pediatrics, College of Medicine<br>and Philippine General Hospital, University of the Philippines,<\/p>\n\n\n\n<p class=\"has-text-align-center\"><a href=\"http:\/\/doi.org\/10.57043\/transnastphl.1997.5930\" data-type=\"link\" data-id=\"doi.org\/10.57043\/transnastphl.1997.5930\">doi.org\/10.57043\/transnastphl.1997.5930<\/a><\/p>\n\n\n\n<p><strong>Abstract<\/strong><\/p>\n\n\n\n<p>Dyslipidaemia is a major risk factor associated with cardiovascular disease among children with insulin-dependent diabetes mellitus (IDDM). Most studies have demonstrated that with increasing poor control of diabetes as reflected by levels of hemoglobin A1c (HbA1c), total cholesterol, total triglyceride and lipoprotein subfractions are likewise increased. This study aims to determine the prevalence of dyslipidaemia among Filipino children with IDDM and further investigate the relationship of dyslipidaemia with glycemic control (HbA1c) and the different variables such as sex, chronologic age, age of onset, dose of insulin, duration of diabetes and blood glucose (FBS).<br>Among 50 IDDM patients studied, 27 females and 23 males, 62% had dyslipidaemia with increased levels of cholesterol, tryglyceride, LDL and decreased HDL. Females were more affected than males (p&lt;0.02). The most common combined plasma lipid abnormality was hypercholesterolemia with elevated LDL (25.7%). Among the diabetic patients with dyslipidaemia, 76.9% were not in good glycemic control. Dyslipidaemia was positively correlated with HbA1c at p&lt;0.043. Cholesterol (r=0.45; p=0.0010), tryglycerides (r=0.31,p=0.0269), and LDL (r=0.56,p=0.0001) were likewise positively correlated with glycemic control. However, no significant relationship was noted with HDL and the other variables such as chronologic age, age of onset, dose of insulin, duration of diabetes and FBS.<br>In conclusion, this study showed that dyslipidaemia is prevalent among Filipino children with insulin-dependent diabetes mellitus notably among those who were not in good glycemic control. It underscores the need for regular lipid monitoring aside from glucose monitoring in order to initiate early intervention to prevent the dreaded onset of cardiovascular complications.<\/p>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\"  class=\"wp-block-file__embed\" data=\"https:\/\/transactions.nast.ph\/wp-content\/uploads\/2026\/03\/TNP-1997-19_23_Dyslipidaemia-Among-Filipino-Children-with-Insulin.pdf\" type=\"application\/pdf\" style=\"width:100%;height:1090px\" aria-label=\"Embed of TNP 1997 (19)_23_Dyslipidaemia Among Filipino Children with Insulin.\"><\/object><a id=\"wp-block-file--media-5e9bbb86-ba89-4490-a7c5-53ad63ecdfa2\" href=\"https:\/\/transactions.nast.ph\/wp-content\/uploads\/2026\/03\/TNP-1997-19_23_Dyslipidaemia-Among-Filipino-Children-with-Insulin.pdf\">TNP 1997 (19)_23_Dyslipidaemia Among Filipino Children with Insulin<\/a><a href=\"https:\/\/transactions.nast.ph\/wp-content\/uploads\/2026\/03\/TNP-1997-19_23_Dyslipidaemia-Among-Filipino-Children-with-Insulin.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-5e9bbb86-ba89-4490-a7c5-53ad63ecdfa2\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Virginia P. Crisostomo, Carmelita F. Domingo, Lorna T. Abad, Sioksoan Cua, Sylvia Estrada, and  Joseph C. Pua<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[835],"tags":[],"class_list":{"0":"post-5930","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-1997-technical-papers","7":"czr-hentry"},"_links":{"self":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5930"}],"collection":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5930"}],"version-history":[{"count":2,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5930\/revisions"}],"predecessor-version":[{"id":6250,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5930\/revisions\/6250"}],"wp:attachment":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5930"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5930"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5930"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}