{"id":5771,"date":"2026-02-20T04:37:27","date_gmt":"2026-02-19T20:37:27","guid":{"rendered":"https:\/\/transactions.nast.ph\/?p=5771"},"modified":"2026-03-26T14:56:29","modified_gmt":"2026-03-26T06:56:29","slug":"research-note-biologically-active-constituents-from-mentha-cordifolia-opiz-leaves","status":"publish","type":"post","link":"https:\/\/transactions.nast.ph\/?p=5771","title":{"rendered":"Research Note: Biologically Active Constituents from Mentha Cordifolia Opiz Leaves"},"content":{"rendered":"\n

Irene M. Villasenor, Jennifer Angelada, Arlyn Canlas,
Deborah Echegoyen
Institute of Chemistry, University of the Philippines<\/p>\n\n\n\n

http:\/\/doi.org\/10.57043\/transnastphl.1999.5771<\/a><\/p>\n\n\n\n

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Abstract<\/strong><\/p>\n\n\n\n

Isolates from yerba buena leaves were tested for their analgesic, antimutagenic, and anthelminthic activities. The acetic acid-induced writhing test showed that isolates \u03b2-sitosterol, \u03b2-sitosteryl-\u03b2-D-glucoside, and cis-8-pentadecenyllactone, at a dosage of 100 mg \/ kg mouse, each decreased the number of squinns induced by acetic acid by 70.0%, 73.0%, and 67.3%, respectively. \u03b2-sitosterol and an unsaturated carboxylic acid derivative are antimutagenic because they inhibited the mutagenicity of tetracycline by 65.3% and 68.7%, respectively, at a dosage of 0\/01 mg\/ 20 g mouse, using the in vivo Micronucleus Test. In vitro tests using Ascaris suum showed that \u03b2-sitosterol is also anthelminthic as the behavior of worms approximate that of the positive controls, Combantrin and Antiox.<\/p>\n<\/div>\n\n\n\n

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Keywords<\/h5>\n\n\n
analgesic<\/a>, <\/span>anthelminthic<\/a>, <\/span>antimutagenic<\/a>, <\/span>Mentha cordifolia Opiz.<\/a>, <\/span>yerba buena<\/a>, <\/span>\u03b2-sitosterol<\/a>, <\/span>\u03b2-sitosteryl-\u03b2-D-glucoside<\/a><\/div><\/div>\n<\/div>\n\n\n\n
<\/object>TNP 1999 (21)_10_Biologically Active Constituents from MENTHA Cordifolia Opiz Leaves<\/a>Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

Irene M. Villasenor, Jennifer Angelada, Arlyn Canlas, Deborah Echegoyen<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[819],"tags":[884,886,885,883,887,888,889],"class_list":{"0":"post-5771","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-1999-technical-papers","7":"tag-analgesic","8":"tag-anthelminthic","9":"tag-antimutagenic","10":"tag-mentha-cordifolia-opiz","11":"tag-yerba-buena","12":"tag--sitosterol","13":"tag--sitosteryl--d-glucoside","14":"czr-hentry"},"_links":{"self":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5771"}],"collection":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5771"}],"version-history":[{"count":3,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5771\/revisions"}],"predecessor-version":[{"id":6053,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5771\/revisions\/6053"}],"wp:attachment":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5771"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5771"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5771"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}