{"id":5131,"date":"2001-01-08T15:13:00","date_gmt":"2001-01-08T07:13:00","guid":{"rendered":"https:\/\/transactions.nast.ph\/?p=5131"},"modified":"2025-02-03T15:29:16","modified_gmt":"2025-02-03T07:29:16","slug":"on-atherosclerosis-and-diseases-of-degeneration","status":"publish","type":"post","link":"https:\/\/transactions.nast.ph\/?p=5131","title":{"rendered":"On Atherosclerosis and Diseases of &#8220;Degeneration&#8221;"},"content":{"rendered":"\n<p class=\"has-text-align-center\">Acd. Conrado S. Dayrit<br>Past President of NAST.<br>Philippine College of Physicians and<br>Philippine Heart Association; Emeritus Professor,<br>College of Medicine, UP<\/p>\n\n\n\n<p class=\"has-text-align-center\"><a href=\"http:\/\/doi.org\/10.57043\/transnastphl.2001.5131\" data-type=\"link\" data-id=\"http:\/\/doi.org\/10.57043\/transnastphl.2001.5131\">http:\/\/doi.org\/10.57043\/transnastphl.2001.5131<\/a><\/p>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>Abstract<\/strong><\/p>\n\n\n\n<p>Twenty-five years ago, in 1876, when this Academy was formed, atherosclerosis or hardening of the arteries was believed to be caused principally by saturated animal fats. This came to be known as the Lipid Theory of Anitzkov, who produced atherosclerotic lesions in rabbit aortas by loading their diet with fat and cholesterol.<br><br>Today, 25 years later, while cholesterol and saturated fats are still of causative importance, we know so much more about this disease\u2014its predisposing, exciting, exacerbating, and propelling causes, its mechanisms of progression and termination\u2014that even if we may not have yet succeeded in completely controlling it, we have an armamentarium of remedies now available to slow its progress, with even more promising remedies, we hope, to be available soon. These advances in knowledge of atherogenesis and &#8220;degenerative&#8221; conditions like arthritis and diabetic complications will be recounted in this paper. The basic underlying processes are genetic (Inheritance), Infection, Immunology, and Inflammation\u2014the I&#8217;s of Human Diseases.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\"  class=\"wp-block-file__embed\" data=\"https:\/\/transactions.nast.ph\/wp-content\/uploads\/2025\/01\/TNP-2001-23-2_16_Atherosclerosis-Diseases-of-Degeneration.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"Embed of TNP 2001 (23, 2)_16_Atherosclerosis Diseases of Degeneration.\"><\/object><a id=\"wp-block-file--media-5562031b-5d39-4419-a9f6-7b47c6556ab1\" href=\"https:\/\/transactions.nast.ph\/wp-content\/uploads\/2025\/01\/TNP-2001-23-2_16_Atherosclerosis-Diseases-of-Degeneration.pdf\">TNP 2001 (23, 2)_16_Atherosclerosis Diseases of Degeneration<\/a><a href=\"https:\/\/transactions.nast.ph\/wp-content\/uploads\/2025\/01\/TNP-2001-23-2_16_Atherosclerosis-Diseases-of-Degeneration.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-5562031b-5d39-4419-a9f6-7b47c6556ab1\">Download<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Acd. Conrado S. Dayrit<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[611,612],"tags":[],"class_list":{"0":"post-5131","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-611","7":"category-2001-plenary-papers","8":"czr-hentry"},"_links":{"self":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5131"}],"collection":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5131"}],"version-history":[{"count":2,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5131\/revisions"}],"predecessor-version":[{"id":5299,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=\/wp\/v2\/posts\/5131\/revisions\/5299"}],"wp:attachment":[{"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5131"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5131"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/transactions.nast.ph\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5131"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}